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Berbamine, bergapten and carveol attenuated over-expressed levels of COX-2, TNF, and NF-b significantly, as shown in Figures 8A,B

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L-arg@MVLs continuously supply L-arginine to immune cells in TME, and selectively achieve L-arginine starvation in tumor tissues by using short hairpin RNA to knock down the tumor arginine transporter CAT-2 expression

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