Methods Network-based identification of natural products Construction of the AD-related pathway-gene network In this study, we aimed to screen AD-related pathways from three perspectives: Most Studied Pathways (pathways with the most literature on AD), Gene-Associated Pathways (derived from AD-associated gene enrichment analysis), and Popular Pathways (pathways showing an increasing trend in the literature)
The pituitary gland, in return, may increase GH levels
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cognitive interviews
Mice were randomized into seven groups: a saline control group (CON), a saline control treated with GHRP-6 (CON + GHRP-6), a doxorubicin-only group (DOX), a doxorubicin group treated with GHRP-6 (DOX + GHRP-6), a doxorubicin group treated with GHRP-6 and the GHSR antagonist YIL781 (DOX + GHRP-6 + YIL781), a doxorubicin group treated with GHRP-6 and the CCR5 antagonist TAK-779 (DOX + GHRP-6 + TAK-779), and finally a doxorubicin group treated with GHRP-6 alongside the CXCR4 antagonist AMD3100 (DOX + GHRP-6 + AMD3100)
149 Quintana-CabreraR.Fernandez-FernandezS.Bobo-JimenezV.EscobarJ.SastreJ.AlmeidaA.et al (2012)