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Reproduction 161 , 343352 (2021)

If you are pregnant, breastfeeding, or under medical supervision, consult your healthcare professional

Distributed under the brand names Geref and Geref Diagnostic, it gained FDA approval in 1997 as a treatment for growth hormone deficiency but was discontinued in 2008 not out of concern for safety or lack of efficacy, but because of manufacturing difficulties.2 3 Yet it remains available in compounded form with a prescription from a licensed healthcare provider

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Centella Asiatica : A wound healing plant with anti-inflammatory qualities

While the RDA is 2.6 mcg, studies show that higher doses of up to 1,000 mcg (1 mg) daily are generally considered safe during pregnancy, especially when treating deficiency [*]