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O is able to either reduce or oxidize transition metals (e.g., iron, copper) ( destroys the Fe-S clusters of proteins, and the reduced iron undergoes additional redox reactions that cause more injuries, as described below ( Hydrogen peroxide As shown in Reaction 2, Fe(II) returns to the oxidized Fe(III) state, in the process catalyzing the production of H 2 O 2

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Their measured glutathione production rate also increased

When consumed orally, glutathione has to be broken down by enzymes in the stomach before it can be absorbed

It can also be considered in cases of resistant melasma or recurrent melasma