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Thus, the only piece of evidence lacking to draw a similar conclusion for GPX1 is a candidate M pro cleavage site , which most algorithms will fail to find, e.g., if they are highly stringent about requiring a Q in the P1 position (Figure 1)

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Measurement of mitochondrial respiratory functions Freshly isolated mitochondria (5 g protein) from GSH depleted with or without NAC treated HepG2 cells were suspended in 1.0 ml of 20 mM KPi buffer, pH 7.4, in the presence of the detergent, lauryl maltoside (0.2%)

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Trimetazidine also increases pyruvate dehydrogenase activity to decrease lactate accumulation [117]