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Issue: No measurable vision improvement after 3 months Potential causes: Unrealistic expectations (expecting improvement vs slowed decline), advanced disease with minimal salvageable tissue, inadequate dosing or inconsistent use, wrong peptide for specific condition, peptides genuinely ineffective for individual, progression monitoring inadequate missing subtle benefits

Bioinformatics 25 , 17541760 (2009)

We review the relevant history and goals

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