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The combination of 968 and PD-L1 has been shown to enhance the bodys immune response to ovarian cancer, and the combination of 968 with the autophagy inhibitor chloroquine (CQ) has been demonstrated to have a synergistic effect on the growth of NSCLC cells [149, 150]

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Clinical translation for using MTAs requires addressing challenges like tissue-specific delivery and long-term safety

Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway

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