As noted, the Wnt/-catenin pathway is a genuine master switch for anagen: stabilizing -catenin in dermal papilla cells accelerates hair growth in experimental models, and the pathways activity distinguishes hair-inducing from non-inducing papilla cells
Changes in sheep wool and active hair-follicle density after FGF5 gene editing in catagen and telogen were also investigated (Supplementary Fig
Preliminary results show that it is possible to develop regulatory profiles for individual countries, though there is considerable overlap
Disclosure of interest: Chak Lam Ip: Nothing to disclose Sooyeon Han: Nothing to disclose Hannah Eskender: Nothing to disclose Agnieszka Dados: Nothing to disclose Arvind Chandratheva: Nothing to disclose Rob Simister: Nothing to disclose Poster Session I - PRE-HOSPITAL SERVICE ORGANISATION 09.00 - PRE-HOSPITAL SERVICE ORGANISATION - 09.01 - PRE-HOSPITAL SERVICE ORGANISATION P199 - ESOC25-2317 FROM SYMPTOMS TO SPECIALIST: OPTIMISING TIA PATHWAYS WITH PREHOSPITAL VIDEO TRIAGE Chak Lam Ip 1 , Agnieszka Dados 1 , Sooyeon Han *1,2 , Hannah Eskender 1,2 , Fahm Deen 1,2 , Arvind Chandratheva 1 , Rob Simister 1 1 University College London Hospitals NHS Foundation Trust, London, United Kingdom, 2 University College London Medical School, London, United Kingdom Background and Aims: National guidelines recommend suspected Transient Ischaemic Attack (TIA) be appropriately managed by a stroke specialist within 24 hours of symptom onset, which is challenging under conventional pathways, where patients in the UK are initially evaluated by Emergency Departments (ED) or General Practitioners (GP) before referral
For ordinal endpoints, NNTs derived by dichotomously collapsing scales are easily calculated but almost always underestimate the amount of benefit a treatment confers
10.1038/nrd4359 Nat
