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Spermidine, in contrast, offers broader systemic benefits, particularly in terms of neuroprotection and cognitive health, while also contributing to overall longevity through its modulation of autophagy

Sulfasalazine and erastin are SLC7A11 and GPX4 inhibitors, respectively

(2000) Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress

Collectively, these findings indicate that the LipoMicel formulation enhances systemic glutathione availability while preserving physiological redox control (i.e., without inducing oxidative burden)

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