The conversation can't just be about benefits
These include inhibiting the JAK2STAT3 signaling pathway, reducing GFAP expression, blocking inflammatory pathways such as NF-B, regulating neurotransmitter secretion such as GABA and modulating APOE expression to control astrogliosis 81,137,138
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In addition, studies report improved bioavailability and a 5080% reduction in oxidative degradation rates [129,130]
Protein J 31:674680 Sogo T, Terahara N, Hisanaga A, Kumamoto T, Yamashiro T, Wu S, Sakao K, Hou DX (2015) Anti-inflammatory activity and molecular mechanism of delphinidin 3-sambubioside, a hibiscus anthocyanin
After discontinuation, recheck serum copper and liver enzymes at 2, 6, and 12 weeks