2c and Extended Data Fig
the published abstract describes this as a safety signal affecting a limited number of patients without a documented breakdown of exact case counts
A recent study demonstrated involvement of radical intermediates formed from hydroperoxides of citronellol in protein haptenation
Further research published in the Journal of Allergy and Clinical Immunology indicates that glutathione depletion may be a key factor in the increased inflammatory response seen in children who frequently use acetaminophen
This is important because unchecked oxidative stress is associated with so many diseases including cancers, neurodegenerative diseases such as Parkinsons and Alzheimers, and heart disease that it can aptly be considered a killer
Morgante G, Darino I, Span A, Luisi S, Luddi A, Piomboni P, Governini L, De Leo