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According to the substitution pattern on the central pyran ring, flavonoids are sub-classified into flavonols, flavones, flavanones, flavan-3-ols, isoflavones and anthocyanins, cf

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However, the side products of the copper redox cycling, particularly hydroxyl radicals produced via the Harber-Weiss reaction, are among the most reactive and damaging forms of reactive oxygen species (ROS) 35