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Such approaches enable direct delivery of therapeutic agents to ischemic regions, alleviating brain tissue injury within a short time frame

For instance, cytosine deaminase converts non-toxic 5-FC into the anticancer agent 5-FU [313]

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Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, igf-I and insulin levels, and increases hepatocyte mif levels and stress resistance