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Dose ranges are often species- and model-dependent, with rodent studies using body-weight-normalized doses (mcg/kg or mg/kg) that may be substantially different from the fixed doses used in primate or pharmacokinetic models

Acute cisplatin ototoxicity paradigm: Under anesthesia, animals received a single intraperitoneal injection of cisplatin (12 mg/kg) over a 30-min period