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Komiyama, Y

She was a young woman with cirrhosis who doctors predicted would die in several years

Mitochondrial metabolic reprogramming in CRC: mechanisms of therapy resistance and emerging interventions As discussed above, CRC cells adapt to hypoxia, nutrient deprivation, and therapeutic stress through mitochondrial metabolic reprogramming, which maintains redox homeostasis and organelle quality control to promote survival

10.1073/pnas.1611406113 42 EmadiA.JunS

Secondly, there is an impaired synthesis of cystathionine from L-serine and homocysteine by cystathionine -synthase, leading to a subsequent reduction in the drainage of homocysteine from the methionine cycle to the transsulfuration pathway

Molecular mapping of twenty-four features of Down syndrome on chromosome 21