10.1371/journal.pone.0074860 PLoS One Summary Keywords ubiquitination, deubiquitination, transcriptional regulation, molecular clock, protein homeostasis Citation Costanzo KM, Prifti MV, Todi SV and Mohan RD (2025) The ubiquitin-proteasome system in circadian regulation
doi: 10.1002/9781394205066.ch4 151 HuS
This supports the idea that similar inflammatory processes can be addressed across different neuroinflammatory diseases
(2) To investigate this, the researchers studied in depth the apparent disruption of FOXO4p53 binding and suggested that by disrupting it, the FOXO4-DRI peptide may shift p53 trafficking toward the mitochondria
Sikiric P, Marovic A, Matoz W, Anic T, Buljat G, Mikus D, Stancic-Rokotov D, Separovic J, Seiwerth S, Grabarevic Z, Rucman R, Petek M, Ziger T, Sebecic B, Zoricic I, Turkovic B, Aralica G, Perovic D, Duplancic B, Lovric-Bencic M, Rotkvic I, Mise S, Jagic V, Hahn V
Promising candidates such as N-acetylcysteine, glutathione precursors, coenzyme Q10, vitamin E, and polyphenols have been found to be potentially effective against oxidative damage and enhancing behavioral outcomes
