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We found a high similarity of gene expression profiles in human and mouse DM tissues
It causes 1015% of acute liver failure in the U.S
Goal: Maintain testicular volume and function during TRT Approach: HCG 500 IU subcutaneously every other day (3x weekly) Begin same time as testosterone therapy Continue for duration of TRT Monitoring: Baseline testosterone, estradiol, LH, FSH Recheck at 6 weeks, then quarterly Adjust based on estrogen response Expected results: Maintained testicular size Preserved fertility potential Possible slight testosterone boost above TRT alone Protocol for fertility restoration on TRT Men on TRT who want to conceive face a decision
HUBERMAN: Within the milieu of the gut, you have a lot of turnover of cells
For example, 2D cultures only allow interactions with neighboring cells and the formation of cell-ECM adhesions on the substrate side in the horizontal plane, whereas in 3D culture, cells are capable of forming adhesions on all sides in a dynamic way [239]