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Collectively, our findings establish a novel link between the oncogene VRK2 and GSH synthesis metabolism, providing a molecular basis for developing stratified metabolic therapies for PC patients

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By the time your next weekly dose is due, enough of the previous dose remains to maintain baseline therapeutic levels while the new dose rebuilds to peak concentration

doi: 10.1038/s41467-017-01965-8 85 TanSKMahmudIFontanesiFPuchowiczMNeumannCGriswoldAJet al