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Thermal hyperalgesia was evaluated using the Hargreaves test, which measures paw withdrawal latency (PWL) in response to a focused infrared (IR) heat source applied to the plantar surface of the hind paw

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297 The most studied cADPRS is CD38, which is the major DNase in cells

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They enhance neurotransmitter activity, allowing better communication between brain cells

This creates space between the skin and the underlying tissues, allowing for better blood flow to the affected areas