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doi: 10.3389/fimmu.2025.1581385 Received 22 February 2025 Accepted 31 March 2025 Published 16 April 2025 Volume 16 - 2025 Edited by Eva Reali, University of Ferrara, Italy Reviewed by Anna Lisa Giuliani, University of Ferrara, Italy Nesimi Uludag, Namik Kemal University, Trkiye Updates Copyright 2025 Zhang, Pan, Sawa, Akaike and Matsunaga