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In some cases, metals like mercury directly inhibit mitochondrial complex activity or trigger calcium overload, leading to mitochondrial swelling and membrane permeabilization (Belyaeva et al., 2011

Furthermore, several xenobiotics that have been shown to promote eryptosis, like lead, paclitaxel, cyclosporine, prostaglandin E 2 (PGE 2 ), curcumin, amphotericin B, dimethylfumerate, and chlorpromazine, can slow down the progression of malarial infection in mice or humans [230, 375, 404, 408,409,410,411]

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Era of biosimilars in rheumatology: Reshaping the healthcare environment