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smegmatis is initiated by trimethylation of the NH 2 group of histidine by EgtD, a SAM-dependant histidine methyltransferase, to yield hercynine

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Groups A-C were associated with significantly increased H3K27ac and H3K4me1 signals around the ATAC-seq peak and groups D-F were associated with significantly decreased signals ( Figure 1C and Supplementary Figure 2 )

HNF4, the master regulator of hepatic genes, is a member of nuclear receptor family of transcriptional factors that is critical for maintenance of hepatocyte identity and specification of hepatic functions 29,30