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Description

The rats underwent a 12-h fast prior to the commencement of the experiment

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An increase in temperature within PDAC tumor tissue drives alterations in lipid metabolism, including a decrease in PUFAs such as phosphatidylcholine plasmalogen (PC-P), attenuating lipid peroxidation and ferroptosis, and further drives gemcitabine resistance in PDAC through the p38-MAPK pathway [154]

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