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A few therapies are approved to treat ALS, but their ability to slow disease progression and extend survival is limited

A local clinic matters because B12 shots are often part of repeat care, follow-up questions, or scheduling around work rather than a one-time urgent event

Concomitant medicines : Clinicians should review all concurrent medications, particularly insulin or sulfonylureas, given the potential for hypoglycaemia with incretin-based agents

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NHS and NICE guidance on weight management focus on sustainable dietary changes, physical activity, and behavioural support rather than supplement timing

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