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For this first analysis, other treatments (e.g., hydroxyurea - see below) were excluded

Age-related considerations Clinical trials included adults across a range of ages, but specific data on elderly populations is limited

Studies into the use of supplemental NAD+ as a form of pain control are still ongoing and the results so far are not yet definitive

Long-term treatment with imatinib results in profound mast cell deficiency in Ph+ chronic myeloid leukemia

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Assessment of schistosomula viability after treatment by NO/ONOO donors Two approaches, methylene blue staining [52] and quantification of lactate production [53], were employed to concurrently evaluate the viability of schistosomula after NOR-5 or SIN-1 treatment