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Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

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Bipolar 1 disorder involves at least one manic episode, with or without a depressive episode or psychosis, whereas bipolar 2 disorder involves depressive episodes with a least one current or past hypomanic episode

Barrier dysfunction is documented and accepted in conditions such as celiac disease and Crohn's disease , and the phenomenon has been studied since the 1970s

In some embodiments, the otic pharmaceutical formulation comprises about 87% by weight of the triglycerides