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Additional preclinical work published in Cell Chemical Biology evaluated NNMT inhibition in similar diet-induced obesity models and confirmed the pattern: significant reductions in body weight gain, adipose tissue expansion, and circulating triglycerides compared to untreated controls

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N-acetylacja to teoretyczne usprawnienie stabilnoci

The most typical side effects are hypotension, dizziness, hyperkalemia, and rare angioedema (Lam 2011)

In turn, these radicals extract hydrogen from PUFAs, resulting in the formation of PUFA radicals (PUFA) [47]