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Thalamus plays a central role in ongoing cortical functioning
This leads to cellular iron overload and induces ferroptosis ( 2+ can be released from heme through the activation of heme oxygenase-1 (HO-1), thereby accelerating ferroptosis ( vs
Diabetes mellitus: the linkage between oxidative stress, inflammation, hypercoagulability and vascular complications
Mechanistically, alterations in gut microbial metabolites such as SCFAs could affect the integrity of the BBB, induce systemic endotoxemia, and activate microglia so as to impact disease progression
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