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Superoxide dismutase 1 in health and disease: how a frontline antioxidant becomes neurotoxic

2022 Aug 8;7(15):e160247

Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness

The crosstalk between distinct RCDs is well documented and can be interpreted through the lens of the cell death-governing intracellular system with multiple redundant backup pathways [20, 142]

Neurotransmitters have either excitatory or inhibitory effects

The superoxide-mediated release of Fe +2 associated with mitochondrial aconitase inactivation has been shown to be a significant source of OH radical formation through Fenton chemistry