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2018 Apr 23;9(5):757-758

In addition, nicotinamide, the primary NNMT substrate 95,96 , is broken down by Lactobacillus arabinosis into nicotinic acid and ammonia 56

Designed to go beyond basic sun defense, this sunscreen also works to prevent the appearance of dark spots and dullness caused by UV exposure

Conversely, isoniazid and pyrazinamide (tuberculosis drugs) are structural analogs of niacin that can interfere with niacin metabolism, potentially precipitating pellagra in rare cases

Once you escalate beyond 2mg per week, the 5mg vial becomes impractical because you burn through it too quickly