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The molecular formula C 27 H 44 N 4 O 5 reflects the presence of carbon, hydrogen, nitrogen and oxygen atoms arranged within multiple amide and aromatic functionalities

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Additionally, co-treatment by tamoxifen and PI3K inhibitor LY294002 synergically induced expression of pro-apoptotic genes such as caspase-3 and -7, and p53 and p21, respectively

Instrument parameters were set as follows: capillary voltage 3000 V, sample cone voltage 35 V, source temperature 110 C, desolvation temperature 320 C, desolvation gas flow 600 L/h, cone gas flow 15 L/h, extraction cone voltage 3.0 V, and collision energy 6 eV