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Colenso-Semple LM, McKendry J, Lim C, et al

Swisher SG , Roth JA, Komaki R, Hicks M, Ro J, Dreiling L, Yver AB, Stevens C, Putnam JB, Jr, Smythe WR, Vaporciyan AA, Walsh GL

IL -1 and TNF - induce neurotoxicity through glutamate production: A potential role for neuronal glutaminase

and Hosaka, Y.Z

However, antidepressants are still sometimes prescribed to help if patients are experiencing depression ( Treating comorbidities ME/CFS displays an overlap with several autoimmune or immune-mediated diseases that also have chronic fatigue as a main symptom, such as Hashimotos thyroiditis (530), fibromyalgia (FM) (532, 554557), Mast Cell Activation Disorder (532), sleep apnoea (532), IBS (532), secondary depression or anxiety (532), Ehlers-Danlos syndrome (532), and PoTS (532, 558563)

Improved Sleep Quality One of MK-677s most well-documented effects is its ability to improve sleep architecture, particularly by enhancing deep sleep the stage where the majority of muscle and tissue repair occurs