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The peptide itself was first identified in human plasma in the early 1970s, and the copper-bound form was recognized shortly afterward as the biologically relevant species in many of the contexts where the tripeptide's activity was characterized

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[PMC free article] [PubMed] [Google Scholar] 65.Luecke RW, Simonel CE, Fraker PJ

Published research on the combination documents that sustained, appropriately-dosed protocols produce measurable elevations in both growth hormone and IGF-1 across multi-week research timelines

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