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The field moves rapidly toward more effective, better-tolerated, and more personalized metabolic therapies

Tanshinone IIA is isolated from Salvia miltiorrhiza Bunge [Lamiaceae] as a diterpene quinone (Fu et al., 2007)

Abstract Reactive oxygen species (ROS) mediate lipid peroxidation and produce 4-hydroxynonenal and other related products, which play an important role in the process of cell death, including apoptosis, autophagy, and ferroptosis

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Subsequently, we employed the incorporation of maleimide-liposomes, renowned for their capacity to disrupt the ROS delivery system, to ameliorate the drugs water solubility and pharmacokinetics, thereby enhancing its ROS-disruptive efficacy