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While cold therapy primarily addresses the acute inflammatory response through physical effects on blood vessels and nerve signaling, BPC-157 works at the cellular and molecular level to promote actual tissue regeneration

Briefly, mice exhibiting the FUSALS phenotype (characterized by FUS translocation from the nucleus to the cytoplasm) demonstrated longer lifespan, reduced disease severity and improved histological patterns when intracellular HSPA1A was overexpressed (Piavchenko et al., 2024