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Limited Human Data A commonly cited human report is a small retrospective case series involving chronic knee pain treated with intra-articular BPC-157, with subjective improvement reported in some patients

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Researchers observed that GHK-Cu influences expression of over 4,000 human genes based on microarray studies, with significant effects on genes involved in collagen synthesis, metalloproteinase regulation, antioxidant defense (SOD, glutathione), and growth factor signaling (TGF-, VEGF, FGF)