This accumulation results in mitochondrial dysfunction, impaired synaptic structure and function, and an imbalance of protein homeostasis
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PLP acts as a cofactor for numerous enzymes involved in amino acid metabolism, particularly those associated with neurotransmitter synthesis, like serotonin, dopamine, and gamma-aminobutyric acid (GABA) (5759)
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This genome-wide regulatory activity is unusual for such a small molecule and suggests GHK-Cu functions as a master regulatory switch in tissue homeostasis
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