Cancer Cell 6 , 6173 (2004)
Alcohol poisoning can lead to coma or death due to slowed breathing, choking on vomit, or severe dehydration
Reports of short-term tolerance exist in small observational settings, yet these reports lack randomized control, large populations, and multi-year follow-up
The assessment of results was made at 24 and 96 hours after peptide administration and included changes in the kidneys on a scale from 0 to 3, where: 0 - healthy kidney, 1 - mild hydronephrosis, 2 - moderate hydronephrosis, visible dilation of the renal pelvis, few changes on the kidney surface, 3 - severe hydronephrosis, dilation of the renal pelvis, thinning of the renal parenchyma, and a significant number of changes on the kidney surface
Any degradation from temperature excursions, improper pH during reconstitution, or exposure to proteolytic enzymes renders it inactive
Hepatocyte growth factor/scatter factor stimulates the Ras-guanine nucleotide exchanger