doi:10.1093/clinchem/42.3.416
European Association for Study of Liver.EASL Clinical Practice Guidelines: Wilsons disease
Pickart estimated lethal dose at approximately 22,500 mg for humans (300-fold above effective doses), with animal LD50 studies in mice showing 8 mg per 25g mouse (320 mg/kg, translating to ~22,400 mg for 154 lb human)
They found that it attaches to special sensors on cells, called receptors, in a way that is similar to a natural hormone called amylin, which helps control appetite
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My orthopedist mentioned surgery as the next step, and thats when I started researching alternatives