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Cell Rep Med (2020) 1:100057

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These findings should be overseen with glutamate as the major excitatory neurotransmitter in the central nervous system (i.e., cognitive functions such as learning and memory in the brain [200], the precursor of major inhibitory neurotransmitter GABA) but excitotoxic neuronal death as a direct result of high concentrations [201], and tight physiologic range that should be maintained [59]

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In addition, it is more effective to treat center-involved diabetic macular edema than photocoagulation surgery and has become the first-line therapy for diabetic macular edema