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In obese rodent models, it promotes lipolysis by breaking down stored fats into free fatty acids without stimulating GH pathways such as IGF-1

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Reduced Inflammation: This peptide has anti-inflammatory properties that help alleviate pain and swelling

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ES2 is a senolytic peptide that targets FOXO4 CR3 but exhibits relatively poorer selectivity for senescent cells compared to FOXO4-DRI 25 (Table S1)