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Exclusion criteria: Patients with acute viral hepatitis, immune hepatitis, Wilson disease , concurrent conditions in which free radical production is elevated like other inflammatory processes outside the liver or intake of antioxidant drugs affecting free radical scavenging such as vitamin C, A and E at time of biopsy

Picomolar to nanomolar activity suggests high receptor affinity and potent biological signalling, which is encouraging for topical delivery where only a fraction of applied compound reaches the follicle

Acknowledgements The authors would like to thank Radiant Research Services Pvt

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Biosensor reveals multiple sources for mitochondrial NAD +