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The GLP-1 boom is largely responsible

Perfect for daily use, it supports long-lasting hydration and helps calm the look of redness, making it suitable for normal and sensitive skin types

Reference: Hsieh et al., 2017 (VEGFR2AkteNOS signalling involvement) VEGFR2 activation triggers: VEGF binding VEGFR2 autophosphorylation (turns on VEGFR2) which leads to PI3K activation which leads to Akt phosphorylation Akt (Protein Kinase B) is critical because it phosphorylates (turns on) eNOS which leads to Nitric oxide synthesis more nitric oxide

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Three trials have reported results as of mid-2026