Keywords: barrier function, celiac disease, tight junction Abstract Larazotide acetate (LA) is a single-chain peptide of eight amino acids that acts as a tight junction regulator to restore intestinal barrier function
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The peptide's primary mechanism involves binding to G-actin monomers, preventing premature actin polymerization and thereby enhancing cellular motility essential for tissue repair
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[28]Edwards BA, Kushner DS, et al
In animal studies, BPC-157 has shown protective effects in central nervous system injury models and nasal peptide delivery can allow compounds to reach brain tissues, so scientists are exploring whether it may help reduce nerve inflammation and support recovery after injury
