10.1053/j.gastro.2016.10.020 52 KassamZ.LeeC
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The topical use of 1,5-dicaffeoylquinic acid (1,5-diCQA) resulted in a dose-dependent decrease in corneal epithelial defects and an enhancement in tear production
From this period, two relevant studies using a larger amount of subjects clearly showed that patients with IBD have an altered intestinal barrier
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Some GPxs are therefore dependent on Se and use GSH as a reducing agent, while others, called TGPx, do not contain Se (NS-GPx) and reduce ROS using thioredoxin, which acts as ROS sensors in various pathways and signal transduction