We recently reported that NNMTi treatment combined with a low-fat, or lean, diet (LD) returned systemic adiposity and liver pathologies of obese animals to the adiposity and liver pathology levels of LD controls
Phase 1: Establish tirzepatide baseline (weeks 1-4) Start tirzepatide alone at 2.5mg weekly
While B12 wont directly burn fat, it plays a vital role in metabolism and energy production
Importantly, animals were singly housed to eliminate the exchange and cross-contamination of intestinal microbiomes, a factor that potentially biases studies with group-housed animals by minimizing microbiome variations for co-housed animals within a cohort
We might change the dose if: Patients dont get better or keep having symptoms of deficiency They keep having trouble absorbing nutrients Their health changes or they get new health problems By watching both lab results and how patients feel, we can make Vitamin B12 shots work best for them
Pyridoxine (Vitamin B6) - Pregnancy and Breastfeeding Warnings
