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For energy metabolism, PLB significantly increased ATP levels in KGN cells, suggesting a positive effect on mitochondrial function, which was reversed by YTHDF1 overexpression (Fig
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Chlorogenic acid inhibits the binding of Nrf2 to its repressor protein Keap1 to activate the Nrf2 antioxidant signaling pathway, thereby preventing APAP-induced hepatotoxicity (Wei et al., 2018)
[DOI] [PubMed] [Google Scholar] 27.Exley C., House E., Polwart A., Esiri M.M
Nonlinearity association between hyperuricemia and all-cause mortality in patients with chronic kidney disease
Using this experimental paradigm, we next determined whether SIRT3 overexpression in HSCs suppresses aging-associated inflammation and tissue function decline by giving rise to progeny that go into the circulation
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