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However, high-dose or prolonged unregulated use has been associated with liver stress in some cases

Effects of 25OHD concentrations on chances of pregnancy and pregnancy outcomes: a cohort study in healthy Danish women

PMID 17520591

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Compared to the control group (0 mol/kg), treatment with berberine in combination with atorvastatin notably decreased serum TC, TG and LDL-C levels in rats (Fig