A potential caveat in this study is that not all women will have poor vitamin B 12 status, and if the proportion of women with adequate status is high, this will reduce our statistical power which may result in failure to detect important differences
Using expired medication can be less effective and may even be harmful
Similarly, although hepatic dysfunction can occur with large niacin doses (1-3 grams daily over months) causing elevated liver enzymes or jaundice, niacinamide at 100 mg is very unlikely to have any adverse effect on the liver
It plays a role in collagen production, wound healing, and even how your body absorbs iron
If you think you may have a medical emergency, call your doctor or 911 immediately
[1] Although water-soluble vitamins are generally excreted through urine when consumed in excess, vitamin B12 is unique in that significant amounts are stored in the liver