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In October 2022, the regulator issued a CRL, requesting additional information and analysis related to the infusion device and drug product across several areas of the New Drug Application (NDA)

However, detailed results from these trials have not been published in peer-reviewed journals, limiting comprehensive assessment of clinical efficacy

This is ingredient-level research context - ProHealth BPC-157 as a finished supplement has not been the subject of an independent clinical study

Other research suggests that conditions like trigeminal neuralgia, which affects the facial nerves, can also improve with B12 supplementation

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